American rock band formed in New York City in 1964. It originally comprised the singer and guitarist Lou Reed, the Welsh multi-instrumentalist John Cale, the guitarist Sterling Morrison and the drummer Angus MacLise. In 1965, MacLise was replaced by Moe Tucker, who played on most of the band's recordings. Though their integration of rock and the avant-garde resulted in little commercial success, they are now widely regarded as one of the most influential bands in rock, underground, experimental, and alternative music. Their provocative subject matter, musical experiments, and nihilistic attitude was also instrumental in the development of punk rock, new wave and several other genres